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Phenylketonuria is a rare autosomal recessive disorder that results in an inability to break down phenylalanine. A person with which genotype(s) would be unable to metabolize phenylalanine? (Note: H represents a dominant allele and h represents a recessive allele)
I) HH
II) Hh
III) hh
Marfan’s syndrome is caused by an autosomal dominant mutation in the FBN1 gene responsible for the production of fibrillin. Due to this mutation people with Marfan’s syndrome have long arms, legs, and fingers with short torsos. Someone with normal body proportions would have which of the following genotypes:
Sickle cell anemia is an autosomal recessive disorder that causes sickle-shaped red blood cells to clump together and block blood flow to parts of the body. A person without sickle cell anemia that is a carrier for the disease has a genotype of:
I) Aa
II) AA
III) aa
Hemophilia A is an x-linked recessive disorder that leads to impaired blood clotting. A woman with the disease would have a genotype of:
Tay-Sachs disease is an autosomal recessive disorder that leads to malformation of the nervous system and leads to death in all cases by or before 5 years of age. A child with the disease would have parents with which of the following genotypes?
Protanopia, an X-linked recessive trait, is a type of red-green colorblindness that result in the inability to perceive red. Which genotypes would result in protanopia?
I) XAXa
II) XaY
III) XaXa
Researchers are investigating the genetic inheritance of a newly discovered disorder. They believe the disorder is inherited in an X-linked recessive manner. Which of the following scenarios would disprove this theory?
Two parents have a child with a rare autosomal recessive disease. If neither of the parents have the disease then both of the parents genotypes must be:
Huntington’s Disease is a rare autosomal dominant disorder. If a person without the disease has a parent with Huntington’s Disease and one parent without the disease then the genotypes of the two parents would be?
A dominant Q allele causes blindness while two recessive m alleles are needed for sight. Which of the following genotypes would NOT result in blindness?