Amino Acid Mutants
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Question 1 of 3
1. Question
A variant protein with the single amino acid mutation, C56K, is most likely to lose which of the following properties?
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Question 2 of 3
2. Question
Sortillin is a 110-kDa protein found in GLUT-4 vesicles and is responsible for transporting proteins across lipid bilayers. It was recently discovered that a variant version of Sortillin (G171A, D223F, and R367E) is implicated in the development and progression of essential tremor.
What is the change in net charge between the wild-type Sortilin and the variant version?
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Question 3 of 3
3. Question
Which mutation is likely to cause the largest disruption of protein secondary structure?
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